The Intrinsically Tenase Complex: A Protein Involved in Cell Signaling and Disease

Target Name: Intrinsic Tenase Complex

NCBI ID: P34548

Other Name(s): None

The Intrinsically Tenase Complex: A Protein Involved in Cell Signaling and Disease

Intrinsic tenase complex, also known as ITC, is a protein that is expressed in various tissues throughout the body. It plays a crucial role in cell signaling and is involved in a wide range of physiological processes. Intrinsic tenase complex has also been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

The intrinsically tenase complex is a protein that is composed of four subunits: ITC1, ITC2, ITC3, and ITC4. These subunits are held together by non-covalent interactions, and they are located in different cellular compartments within the cell. ITC1 is the N-terminus of the complex, and it is responsible for the formation of the complex and for its stability. ITC2 and ITC3 are the middle subunits, and they contain the catalytic domain that is responsible for the chemical reaction that occurs within the complex. ITC4 is the C-terminus of the complex, and it is responsible for the regulation of the complex's activity.

The intrinsically tenase complex is involved in a wide range of cellular processes that are essential for the survival of the cell. One of the most well-known functions of ITC is its role in cell signaling. The complex is involved in the regulation of various signaling pathways, including the TGF-β pathway, the PI3K/Akt pathway, and the NF-kappa-B pathway. These pathways are involved in the regulation of cell growth, differentiation, and survival, and they play a crucial role in the development and progression of many diseases.

In addition to its role in cell signaling, the intrinsically tenase complex is also involved in the regulation of various cellular processes that are important for the structure and function of the cell. For example, ITC is involved in the regulation of cell adhesion, which is the process by which cells stick together to form tissues and organs. The complex is also involved in the regulation of cell migration, which is the process by which cells move from one location to another in the cell.

The intrinsically tenase complex has also been identified as a potential drug target and biomarker for a wide range of diseases. For example, ITC has been shown to be involved in the development and progression of cancer, and it has been identified as a potential therapeutic target for cancer. Additionally, the complex has also been shown to be involved in the development and progression of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

In addition to its potential therapeutic applications, the intrinsically tenase complex is also an attractive biomarker for the diagnosis and monitoring of various diseases. The complex is expressed in a variety of tissues and cells, and it can be used as a protein biomarker for a wide range of diseases. For example, ITC has been used as a biomarker for diseases such as cancer, neurodegenerative diseases, and autoimmune disorders.

Overall, the intrinsically tenase complex is a protein that is involved in a wide range of cellular processes that are essential for the survival of the cell. It has also been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Further research is needed to fully understand the role of ITC in these diseases and to develop effective therapies that can treat them.

Protein Name: Intrinsic Tenase Complex

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